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Farrior75
Multiple Myeloma Discussion • 6d ago
IgA Lambda with t(11;14)
I’m hoping to connect with others who have IgA lambda multiple myeloma with the t(11;14) translocation, or anyone with t(11;14). My mom has IgA lambda with t(11;14), and I believe she may be approaching progression, so I’m trying to learn as much as possible to help my family make the best decisions regarding which treatments to pursue and in what order. As many of you probably know, t(11;14) is a somewhat unique subtype of myeloma and is classified as standard-risk. However, after doing a significant amount of research and speaking with other patients on different platforms, I’ve heard very mixed experiences with the traditional frontline approach D-VRd followed by transplant. Some people with t(11;14) have told me that treatments such as CAR-T or venetoclax-based therapy ultimately gave them their deepest response or longest remission. I would especially love to hear from anyone here with t(11;14) who has already gone through treatment. Which treatment worked best for you and how long did your remission last? I understand that everyone’s disease and treatment response can be different, but hearing real experiences from people with the same translocation and subtype would mean a lot to me and my family.
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