I have been receiving Darzalex Faspro shots since November 2024. I am not happy with the results. I am currently taking Pomaylst 3mg too. It dropped my m-spike by 25% and cut my Lambda Light chains in half but they are still elevated. My last blood test showed a drop in my Kappa light chains to the point of them being low. My specialist is ok with a wait and see approach I don't think I am. I am considering switching out the Pomalyst for either Kyprolis or Velcade. I have been on Kyprolis before and it did work and realize it is an infusion. I would like to be on the most effective but yet least cumbersome treatment and of course the least side effects. My understanding is the Velcade is weekly shots where the Kyrpolis is 3 weeks on and 1 week off. Any thoughts?