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mhmadani
Multiple Myeloma Discussion • March 26, 2025
Wondering About ASCT After MRD Negative?
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Hello everyone, I am 43 years old male, and I was diagnosed with Multiple myeloma primary plasma cells leukaemia free light chain back in November 2024, when I started feeling lower back pain and I ended up in ER after a VCF in my spine. All tests was done when admitted to the hospital, and my journey started with this disease. At diagnosis my FLC ratio was at 31, and almost back to normal after completing 2 DARA VRDC cycles. Fish is negative. CD56 marker is negative. Plasma cells in peripheral blood was 16%, and in bone marrow 19%. After completing cycle 2 plasma cells were undetectable in peripheral blood and less than 1% in bone marrow. After completing cycle 3 I was able to achieve MRD negative. The treatment plan is to complete 6 cycles of DARA Vrdc as an induction phase, and consolidate it with an autologous transplant (stems collection was done post cycle 3). As Currently I am undergoing cycle 6, and the autologous is scheduled mid next month, I am wondering if in my case this is the best possible course of action.. I need opinions please 🙏🙏
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