I had CAR-T on 2/22/23. I did well post treatment with Stage 2 CRS (temp 101.4 and falling blood pressure) on day 7. I was treated with Toci and immediately recovered. My remaining recovery was as expected until Day 40 when I experienced an inflammatory arthritis of my right elbow and knee. It was quite painful and debilitating. I was treated with a short course of steroids and slowly returned to the expected level of side effects. Unfortunately, I have had 2 repeat episodes of inflammatory arthritis since though these have been less intense. I was seen by an orthopedic specialist during one of these episodes and given a steroid injection into the knee that gave relief for 6 days and then returned. I am now being told that I need a knee replacement as it appears that I have no cartilage with bone on bone in the right knee. Prior to CAR-T I have had no arthritic symptoms and no knee issues. It is suggested that the inflammatory arthritis caused destruction of the cartilage. I have been in touch with another CAR-T recipient who had arthritic complaints before his procedure but his arthritis significantly worsened following treatment. He is now scheduled for knee replacements of both knees. I have found very little in the literature about inflammatory arthritis post CAR-T. I am wondering if this occurs more than is presently recognized. Please share your experiences.