Pangea vs. Mayo 20-2-20 Model Hi. Newbie here. VERY thankful to find this group! Diagnosed with HRSMM earlier this summer. Just starting, really. Have had just one conversation with an MM specialist. He used the Pangea model vs. the Mayo Clinic's 20-2-20 model in thinking through my situation (active surveillance). The Pangea 2.0 model is a VERY different progression % for me than Mayo Clinic's. (My M-spike is just over 2.0 and I have a 1Q gain and some other chromosomal abnormalities). Has anyone else had this experience of comparing the prognosis models and scratching their heads?