I am new to this group. I am 58 years old. I was diagnosed with MGUS in 2017. My Kappa Lambda ratio then was about 9. My M-Spike was around 1 and my PET Scan was normal. My Bone Marrow Biopsy showed 5% cancerous plasma. My numbers slowly increased in general for first 3-4 years. Since then the pace of increase has accelerated. My last labs showed my ratio passed 100 (118) and M Spike is at 2.35. Had a PET Scan in October 2024 which was clear. I have not had another bone biopsy since my first in 2017. My myeloma doctor at MSKCC said if my Kappa goes above 50 (at 46 now) he will order one. He said with my hemoglobin at 13 he didn't think there was heavy involvement in bone marrow. I feel fine with no symptoms and swim daily for 45 minutes. Perhaps I've been googling too much but I thought that a ratio above 100 meant active myeloma but honestly I have no idea if I'm considered at MGUS or Smoldering stage. My doctor at Sloan said light chain ratio is not the most important marker. I should mention I have Ig G Kappa. Anyone else have similar numbers and also not taking treatment? Just reading about all the GI issues with Revlimid are worrisome to me as I know this is used in induction therapy. Has anyone in here not experienced GI issues using Revlimid? Thanks in advance for your comments.