64 yo. Newly diagnosed MM. Taking DVRd regimen. A few days ago, my hands started itching like crazy, keeping me up for hours at night. EDIT: I spoke to my doctor. He thinks the itching is from heightened liver functions, which seems to be from some of the meds I am taking. He gave me something to take and I also take benadryl before I go bed. My itching has pretty much stopped. I don't know if it's part of the expected neopathy, but it's not that I have lost feeling in my hands ir feet. My hands tingle and itch and I cannot figure out what to do. It has kept me up for literally hours and hours at night. During the day, it seems to come and go, but when I lay down -bam. Its 1am where I am and have been up since 11pm when I tried to go to sleep.