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AlanP
Multiple Myeloma Discussion • May 27, 2025
Confusing Results: M-Spike but Negative BMB?
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I am MM patient since 2020. After 4 lines of therapy I had CAR-T in July 2023. A few months back I had labs every month, Jan, Feb and March. That was 3 sets of labs at Mayo and another set at Moffit. All 4 sets of labs reflected a M-Spike of .3. While not high, my MM doc did state that I was definitely slowly relapsing. Same was stated by the Moffit doc. On 7 April I had a BMB and additional set of labs both of which came back negative for active disease. No good explanation from my doc. Does anyone have an opine as to how that could happen?
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