I have Multiple Myeloma and Amyloidosis. When I was getting treatments for several months, my joints started making grinding, popping and cracking noises. I told my doctors about it but they didn't seem concerned. After my treatments and stem cell was done, my joints kept on making the grinding noises. I thought in a couple of months to a year it would stop but it never did. It's a little over 4 years since my stem cell transplant and I found out that my right knee is getting a full knee replacement. Before my treatments I never had any problems with any of my joints. They said I have bad arthritis in my right knee and it really damaged the bone. I'm just wondering if the treatments caused my arthritis to begin with. I guess I'll never know for sure but was just wondering if anybody else is going through the same thing.