Community post
MRD Negative Possible with Positive Biopsy?
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Good evening!
I recently completed four cycles of DVRd after being diagnosed with MM presenting with slight anemia, but no other CRAB criteria. I have achieved MRD negativity in my blood, and other numbers such at B2M, MSpike, FLC, etc. seem to be returning to normal.
I’m awaiting the results of the ClonoSeq on my bone marrow. However, my BM biopsy results still report plasma cell neoplasm. Is it possible for the ClonoSeq to return MRD negativity with the bone marrow biopsy exam still showing this?
I’m wondering if those MM cells are still in the process of dying off.
Thank you!
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