So here is a question I have and I know it's been widely debated and likely will continue to be debated. The question is whether ASCT is still strongly supported by myeloma experts or is the trend moving toward collecting stem cells and freezing them for a future ASCT if needed? Anyone who chose to defer transplant and now regrets it or anyone who chose transplant and now wishes they had not had one. A clinical trial that has been offered requires the ASCT so there is no pulling back from this versus doing quadruplet therapy and then based on MRD negativity having the option of doing ASCT or deferring for later treatment.