I was diagnosed with MM in October of 2021 I did 5 cycles of RVD and a SCT in March of 2022. Labs looked great by April 2022 and I’ve been considered in complete response and MRD negative. As is common, my immunoglobulins have been low ever since my SCT. When diagnosed my IgAa was over 8000. Since my SCT it has been anywhere between 7-14. My IgG is also low and I’ve been getting IvIG when my levels are below 550. I can usually get two months of normal levels with a treatment. My oncologist told me that sometimes the treatments can also help the IgA. But that hasn’t happened. About six weeks ago I started taking a probiotic thinking it might help with some acid reflux/heartburn. Last week I had my 3 month full lab panels. After getting the results I was very surprised to see my IgA levels was just 3 points below normal at 47. I found this intriguing so I googled asking if probiotics can help IgA levels. It revealed that it is possible. (And yes I am very open minded about what I read on google knowing it can be very outdated) So my question is, has anyone else had this observation? I would like to study this in more depth but not sure how to go about it. And my oncologist at a previous appointment shrugged off this possibility when I asked about taking an IgG supplement I had come across. At the time I did not realize that this supplement was a probiotic. In the meantime I started a different brand. I’ve heard many times that illnesses often are a result of gut bacteria. I only get my IgA checked every 3 months, so I won’t have another result until November but I am very curious to see if this was just a fluke or if it perhaps is something to be encouraged about. I do get my IgG checked monthly and I’m hoping it improves it also to the point I can avoid the IvIg infusions as often. Obviously this wont change that I am living with MM but if it can help my immune system I am all for that. Anyone have any of their own experience to share?