Hi everyone, hope you are all doing well. I wanted to ask a few questions about monitoring while in PR or VGPR and would really appreciate your experiences. For those who are in PR or VGPR: 1️⃣ How often do you get your M-spike and free light chains checked when things are stable? Is it every cycle, or does the testing interval become less frequent over time? 2️⃣ Do your numbers sometimes fluctuate up and down from one test to the next? If yes, what kind of variation have your doctors told you is considered normal or not concerning? 3️⃣ At what point do you and your medical team feel a drug may be losing effectiveness? Is resistance concluded only after several rising results, or can it be identified quickly? I would be grateful to hear how others have experienced this part of the journey. Thank you so much for sharing.