After 2 treatments with Revilimid (6 years) then Daratumamab ( less than 2 years) I was placed om Cyclophasphamide. To say I experienced extreme fatigue is an understatement. After 2 months they realized that it wasn't working. Not only that but my light chains shot way up. But this has been the gift that keeps on giving. I noticed that when I started to take this drug my belly became very bloated and uncomfortable. It presses against my diaphram and makes me very winded. Although I am now on Carflisomab ( with good results) my belly remains bloated. I am seeing GI specialist for this, but so far no go. Some others have suggested SOBI which is a small intestine bacterial infection, but I dunno. Anybody ever have this weird side effect?