Does anyone else suffer a transient, post exertional malaise? I am 3 years post ASCT and on a 21:7, 25mg Lenalidomide, 20mg dexamethasone regime. I take the dex on a Friday morning and on a Saturday could do a 20km bicycle ride equivalent without much concern. If I cycle 20km on Sunday morning however I will collapse by the afternoon and this may continue through Monday and Tuesday. If I don't exercise on the Sunday then I am happily able to cycle 50km Tues, Wed, Thur & Fri. For the first two years of maintenance I never had this problem though I had Covid a year ago so I'm trying to figure whether it might be that or possibly development of a dexamethasone related adrenal insufficiency? If you've gone through the same I'd be very interested to learn.