My MGUS, diagnosed in 2017) progressed to high risk smoldering myeloma in early 2025. It has likely progressed to active myeloma or darn close according to my labs. My labs have been showing steady increases in IgG Kappa light chain ratio and it's at 238 now ( was 188 6 weeks prior) but my Calcium, Kidney function, and Hemoglobin have been normal. My latest hemoglobin dropped to 12.5 from 13.3 six weeks prior. So here's my question. I have felt in the past two weeks tingling in my toes and feet which has become more continuous now. I feel it more in my left foot rather than right foot. I have sent a note to my myeloma doctor at MSKCC earlier today. I am concerned that it may be amyloidosis but i also know it can come with myeloma. I will have a PET scan in 10 days and repeat blood work in a bit less than 4 weeks. My last MRI in mid July showed no lesions. If anyone with just Multiple Myeloma and Myeloma plus amyloidosis could weigh in as to whether this symptom raises a red flag of amyloidosis? I may be starting treatment sooner rather than later as per my doctor.