I am curious to hear if anyone has had the serious muscle and joint pain and weakness on V. It has been terrible for me. I've gone from a very active, outdoor, energetic woman to one who has fallen several times, can barely climb one set of stairs, painful to kneel down or get up from the ground. This started at 3 months in and has continued even after being off the drug for 6 months. My Oncologist tells me that often these side affects don't go away ever. I live in the country, have raised horses for years, busy with yard work, a swimmer until taking the drug. Any suggestions other than light exercise? Since this problem started, I have actually fallen and fractured my kneecap because I have lost so much strength in my legs. This has actually changed my life in very unpleasant way. I am doing OK with the CLL, was first diagnosed in 2016. Only a couple of bad times when the WBC's got really low. Just wondering why they didn't mention this side affect when I started the drug and if anyone has heard if they have found a solution for this. I read the suggestions but no one seemed to have had the reaction I have had to taking V.