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Suzukiviolin25
Multiple Myeloma Discussion • December 22
Question for those with t(11;14) and quadruplet treatment (Dara KRD)
I am now midway through cycle 2 of Dara KRD and I have translocation (11;14). I've heard so many different things about this from various myeloma experts. One of things I have heard is that this cytogenetic feature may not respond as well to quadruplet induction therapy. I'm just curious to find out if anyone has this same translocation and how they have responded to quadruplet therapy. Did you achieve MRD negativity (without transplant)? I do know that Venetoclax is very effective but only available after first line of treatment for those with this cytogenetic feature. I also know MM is not the same in any two individuals but I am curious to hear how you all fared.
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