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After CAR-T Fail: Tough Side Effects & Bispecifics?
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My husband has high risk MM. He has his SCT last May, but after 10 months relapsed. He was heading to CarT treatment, but the day the cells were supposed to be returned to the clinic, we learned that the T cell modification had failed. His cells were slow growing, did not respond well to the growth factor treatment, and failed transduction with the virus.
He’s currently on Xpovia, dexamethazone, and carphilsamide. However, the side effects have been hard to deal with. I’m wondering if anyone has had a similar reaction. Can he move to bispecifics relatively soon, or does he have to wait for the current treatment to fall? Because as far as he’s concerned, it’s not worth doing as it stands.
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