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MHolden
Chronic Lymphocytic Leukemia Discussion • May 14, 2025
Managing Calquence Headaches: Tips?
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Hey y'all! This is my first post on this platform. I'm 41 YO with High Risk CLL with complex karyotype, specifically the dreaded TP53 mutation. Sound effects Dun dunn duuun. My husband,who travels for work, and I have a busy 9 year old who is the best kid -fun, kind, helpful, supportive, and silly. I just started Calquence (acalabrutinib) and have been at full dose about a week and a the half. So far overall I'm feeling much better and labs are looking like they're moving in the right direction. The problem is I wake up with these awful headaches, like I can't see straight. I'm working hard to stay hydrated which often means waking up around 3-5 am to use the bathroom and the headache has already started. Caffeine is recommended and helps once I'm up for the day, but I can't take it for my middle of the night wake ups. The headaches make it really difficult to get moving in the morning to be present for my kiddo, so I'm testing out new morning routines for that. Any suggestions for the headaches that won't keep me from getting back to sleep? Any morning routines that have worked well for anyone else? Thanks!
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