Neuropathy - Feet Since my initial rounds of Kyprolis the front third of both feet have very minimal feeling. As a result I watch my foot care very closely but that did not prevent nail fungus as a result of a lowered immune system (Treating with laser treatment and all is well). Thinking I was watching my feet closely I stepped out of the shower with light color blood emanating from my left foot. Turns out I had developed a big ole blister between the foot pad and base of toes. With no feeling in that area the blister top had opened and torn off leaving a single layer of very red skin. Anyone else have similar foot issues?