Community post
Experiencing Light Chain Spikes After COVID?
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Hi all -
I recently went through a bout of Covid. It was quite different from the one other time I had it, with nasal congestion, some fever, fatigue, and major coughing. It lasted for about a week, and I recovered well. Shortly after recovering, I had my labs done and noted to my surprise, that my lambda (involved) light chain number shot up from about 16 mg/L (well within normal) to 157 mg/L (WAY above normal) with my kappa:lambda ratio dropping to 0.12 (way below normal). Those tests were run only a month apart from each other. My M-spike stayed at the 0.4 level it's been at since my last stem cell transplant, over a year ago. This was, of course, very concerning. I messaged my doctor and she had me wait a week and then repeat the tests. After just two weeks or so, my lambda light chain level dropped to 46 mg/L, a little above normal, and the kappa:lambda ratio went up to 0.43, within the normal range. And for the kicker, the M-spike dropped to 0.1. So basically, over the course of a few weeks, I went from normal to way high lambda light chain results back down to close to normal. The M-spike stayed where it had been and then suddenly dropped significantly. My doctor has no explanation for this and has never seen anything like it. My question is whether any of you have experienced any similar weirdness with your light chain numbers during or after a Covid infection (or any other infection for that matter).
Thanks very much,
Mike
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