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Chromosomal and Gene Abnormalities in Myeloma
1. BETA - Why is it important for a patient to know the genetics of their myeloma? How is risk determine in myeloma?
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BETA - Why is it important for a patient to know the genetics of their myeloma? How is risk determine in myeloma?
Quiz
2. What is the definition of high-risk Multiple Myeloma (HRMM)?
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What is the definition of high-risk Multiple Myeloma (HRMM)?
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3. What chromosomal abnormalities are considered high-risk, standard risk?
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What chromosomal abnormalities are considered high-risk, standard risk?
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4. BETA - What is meant by hyperdiploid myeloma? How does this affect risk?
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BETA - What is meant by hyperdiploid myeloma? How does this affect risk?
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5. BETA - What is a 1q gain? How does this affect risk of progression?
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BETA - What is a 1q gain? How does this affect risk of progression?
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6. Why is chromosome 14 a site of high-risk myeloma genetics? What is the job of Chromosome 14?
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Why is chromosome 14 a site of high-risk myeloma genetics? What is the job of Chromosome 14?
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7. What is a 17p deletion? Why is Del of 17p considered high risk?
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What is a 17p deletion? Why is Del of 17p considered high risk?
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8. Can only a percentage of your myeloma cells possess 17p deletion? How is that percentage determined?
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Can only a percentage of your myeloma cells possess 17p deletion? How is that percentage determined?
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9. Can only one allele of chromosome 17 have a deletion? How does this affect risk?
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Can only one allele of chromosome 17 have a deletion? How does this affect risk?
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10. BETA - What does it mean if you have a mutation in chromosome 17 and a deletion?
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BETA - What does it mean if you have a mutation in chromosome 17 and a deletion?
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11. Will Del17p and other chromosomal abnormalities go away after an auto ASCT? If not why may it not be detected?
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Will Del17p and other chromosomal abnormalities go away after an auto ASCT? If not why may it not be detected?
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12. What are genetic sub groups in myeloma base? What testing is done to identify sub-group?
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What are genetic sub groups in myeloma base? What testing is done to identify sub-group?
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13. BETA - What is the 11, 14 translocation?
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13. (Guest Lecture): Risk Classification | HealthTree Foundation Round Table on Genetics
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(Guest Lecture): Risk Classification | HealthTree Foundation Round Table on Genetics
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14. BETA - What is p53?
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14. (Guest Lecture): Myeloma Sub-Population Genetic Characteristics | HealthTree Foundation Round Table on Genetics
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15. BETA - Do all patients who have deletion of 17p have the same risk?
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15. (Guest Lecture): Audience Questions & Answers | HealthTree Foundation Round Table on Genetics
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16. BETA - What are genetic sub groups in myeloma base? What testing is done to identify sub-group?
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BETA - What does it mean if you have a mutation in chromosome 17 and a deletion?
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