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Dave Braucht
Multiple Myeloma Discussion • February 14, 2024
Sharing a Fun Take on Our Immunoglobulins
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Happy Valentine’s Day for my fellow Warriors. I hope this brightens your day about something we take seriously in our broken body. I hope you enjoy. If it makes you smile, I’ve accomplished my goal…. In the bustling city of Immunopolis, five superheroes patrolled the streets, each with a unique power to keep the citizens safe from invaders. Meet the Fab Five Immunoglobulins! IgG, the General: Towering like a seasoned captain, IgG, the most abundant (75%), was the city's stalwart defender. He patrolled tirelessly, neutralizing bacteria and viruses like rogue robots with his powerful antibodies. His motto: "No germ gets past me!" IgM, the Scout: Ever quick and agile, IgM (10%) zipped through the alleys, her many arms reaching everywhere. She detected new threats early, like a watchful scout, alerting the team with her "Danger!" cries before foes could cause widespread damage. IgA, the Guardian: IgA (10%), the friendly neighborhood hero, stood guard at every mucosal gateway, from the eyes to the gut. Like a skilled bouncer, she screened incoming molecules, letting good ones in and bouncing bad ones out, keeping the citizens healthy and infection-free. IgD, the Strategist: Residing in the B-cell headquarters, IgD (less than 1%) was the brains of the operation. Though rarely seen, he strategized, deciphering enemy weaknesses and guiding the team with his tactical brilliance. He ensured every battle was meticulously planned and executed. IgE, the Sentinel: IgE (less than 0.1%), the most controversial hero, had a trigger-happy finger (or rather, molecule). He served as the allergy alert system, sounding the alarm with histamines (itchy warnings) for even the slightest foreign substance, sometimes causing unnecessary chaos. But when a truly dangerous allergen appeared, his swift response saved the day. Together, the Fab Five Immunoglobulins, despite their occasional squabbles (IgE blaming IgG for being too rough, IgA wishing IgE wouldn't overreact), protected Immunopolis with unwavering dedication. They taught everyone that immunity wasn't just about brute force but about teamwork, vigilance, and understanding each other's strengths and weaknesses. So remember, the next time you feel healthy and strong, thank the Fab Five for keeping you safe and sound! — feeling inspired.
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cyanSquirrel
Multiple Myeloma Discussion • February 14, 2024
Experiences with Mezigdomide in a Trial?
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Do we have in this group a member that gets Mezigdomide insteads Rev (in a research) . Together with Daxa and Valcaid . If yes, will glad to learn if it helps . Is it 1mg ? And what are the side effects ? Thanks
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fuchsiaBear
Multiple Myeloma Discussion • February 13, 2024
High IgG/Kappa With Otherwise Normal Labs?
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Hello! I was diagnosed with Smoldering Myeloma a couple of years ago. Bone marrow had 12% bad cells and my IgG has always been slightly high. Other than that, my blood work has been normal. I had my blood work done and a follow up tomorrow afternoon. I just reviewed the numbers all is in the normal range besides, IgG is 1699, Keppa 3.98 and Kappa/Lambda is 2.65. Has anyone else experienced normal range on all other blood work but these? Just need some reassurance. Thanks, Julie