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Thumbnail for Is myelodysplastic syndrome a myeloproliferative neoplasm? What are myeloproliferative neoplasms? Can an myeloproliferative neoplasms also turn into acute myeloid leukemia?
Playlist: MDS Progressing into AML

Is myelodysplastic syndrome a myeloproliferative neoplasm? What are myeloproliferative neoplasms? Can an myeloproliferative neoplasms also turn into acute myeloid leukemia?

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tonkawonka
Multiple Myeloma Discussion • July 20, 2024
Managing New Joint Pain Post-Transplant?
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Hello! I have Kappa Light Chain myeloma, high risk. I had four rounds induction with RVD and first stem cell transplant in September, second in February. Both were auto transplants. During the second, I got sepsis and was put on meds to increase blood pressure, midodrine and fludrocortisone. After I came home, I started developing joint pain. Started in elbow and pinky on left hand, then spread. I have pain in fingers, elbows, knees, and bottom of feet. Worse first thing in morning. Doctor took me off the fludrocortisone about 6 weeks ago, didn't help. Last week decided it could be the Bactrim, so they took me off that as well. So far, no changes. Fingers do swell somewhat overnight. Any ideas? Next step would be Rhuematologist.
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rubyCrocodile
Multiple Myeloma Discussion • July 19, 2024
Concern Over Rising Light Chains, Normal Ratio?
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Hello, I am at day 79 post SCT. I did my labs around day+60 and both free light chains were within range and ratio was at 1.12. Three weeks later, I did my labs again and the light chains doubled and are above the range. Both Kappa and Lambda were at around 28 mg/L. The ratio is at 1.02. Does this mean my I am relapsing?
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rubyCrocodile
Multiple Myeloma Discussion • July 19, 2024
Concern About Rising Light Chains Post-SCT?
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Hello, I am at day 79 post SCT. I did my labs around day+60 and both free light chains were within range and ratio was at 1.12. Three weeks later, I did my labs again and the light chains doubled and are above the range. Both Kappa and Lambda were at around 28 mg/L. The ratio is at 1.02. Does this mean my I am relapsing?
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Secops808
Multiple Myeloma Discussion • July 19, 2024
Considering ASCT: Is It Still Necessary?
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Thoughts on ASCT? I am standard risk, diagnosed 6 months ago, have been on CyBorD. With all the advancements in treatments, I am wondering if it is really necessary for ASCT/harvesting. I have heard that some MM specialists even not recommending ASCT since there are so many other lines of therapy now, compared to 10+ years ago. Looking forward to hear some thoughts on this topic! Have a great weekend everyone!