Questions to Ask About Gallbladder Cancer

By Katie Braswell
Posted by
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HealthTree
Last updated and reviewed on: October 28, 2026

Questions about your diagnosis

  • What type of gallbladder cancer do I have?

  • What did my pathology report show?

  • How large is the tumor?

  • What grade is my cancer?

  • Has the cancer spread outside the gallbladder?

  • Should my case be reviewed by a multidisciplinary cancer team?

  • Should I get a second opinion at a center experienced in hepatobiliary cancers?

Questions about staging

  • What stage is my gallbladder cancer?

  • Has it spread to the liver?

  • Are nearby lymph nodes involved?

  • Has the cancer spread to distant organs?

  • What imaging tests do I need?

  • Is my cancer considered resectable or unresectable?

Questions about surgery

  • Am I a candidate for surgery?

  • What type of operation would I need?

  • Will part of my liver need to be removed?

  • Will lymph nodes be removed?

  • What are the risks of surgery?

  • How long will recovery take?

  • What is the likelihood of removing all the cancer?

  • Will I need chemotherapy or radiation after surgery?

Questions about chemotherapy

  • Do you recommend chemotherapy?

  • Which medications would I receive?

  • What is the goal of treatment?

  • How long will treatment last?

  • What side effects should I expect?

  • How will we know whether treatment is working?

  • What happens if the cancer progresses?

Questions about immunotherapy

  • Am I eligible for immunotherapy?

  • Would durvalumab or pembrolizumab be appropriate for me?

  • Would immunotherapy be combined with chemotherapy?

  • What side effects should I watch for?

  • How long would immunotherapy continue?

  • Do I have any medical conditions that could affect my eligibility?

Questions about biomarker testing

  • Has my tumor undergone comprehensive molecular profiling?

  • Was my tumor tested for HER2 alterations?

  • Do I have any actionable mutations?

  • Are there targeted therapies that might work for my cancer?

  • Should I consider a molecularly targeted clinical trial?

Questions about prognosis

  • What does my cancer stage mean for my prognosis?

  • Is the goal of treatment to cure the cancer or control its growth?

  • What factors are most important in predicting my outcome?

  • How might my prognosis change depending on treatment response?

  • What symptoms should prompt me to contact your office?

Questions about clinical trials

  • Are there clinical trials available for my type of gallbladder cancer?

  • Would a clinical trial be appropriate now or after standard treatment?

  • Are there studies available at other cancer centers?

  • What are the potential benefits and risks?

  • Would participation require travel?

Questions about supportive care

  • How can I manage abdominal pain?

  • What should I do if I develop jaundice?

  • Can I meet with an oncology dietitian?

  • What can help with nausea and appetite loss?

  • Should I see a palliative care specialist?

  • Are there resources for financial or transportation assistance?

  • What support is available for my family?

The Basics: Asking questions can help patients understand their diagnosis, compare treatment options, and make informed decisions with their healthcare team.