Muscle, joint, and bone pain are common for people living with lymphoma, especially after CAR-T. There are several reasons why this can happen:
Bone marrow involvement. Lymphoma cells can collect in the bone marrow, causing pain in the bones and joints.
Side effects from treatment. CAR-T can increase inflammation, leading to soreness in muscles and joints.
Other health issues. Conditions like arthritis or osteoporosis may also cause joint or bone pain in people with lymphoma.
Fatigue. Tiredness from CAR-T or the cancer itself can sometimes lead to body aches and muscle discomfort.
How to manage pain after CAR-T for lymphoma
There are several ways to reduce muscle, joint, or bone pain and improve comfort:
Medications
Prescription pain medicines or anti-inflammatory treatments may be prescribed by your doctor.
Topical ointments and patches that you can get at your local pharmacy can provide some relief, but should be discussed with your medical team before use.
Bone-strengthening medications may be used if needed.
It is important not to use tylenol or NSAIDs (such as ibuprofen, aspirin, or naproxen) unless first discussed with your health care team as these medications can mask a fever or infection and impact the function of platelets in your blood.
Physical therapy and movement
Try gentle stretches and exercises to improve strength and flexibility.
A physical therapist can show you safe movements to reduce pain and stiffness.
Supportive therapies
Use warm or cold packs to ease sore areas.
Make ergonomic changes at home, like using supportive chairs or cushions to protect your joints.
Complementary therapies
Consider acupressure to relieve pain without medication.
Massage therapy can help relax tight muscles. Be sure to let your massage therapist know that you are on cancer treatment and may have low blood counts.
Try gentle mind-body practices like yoga, meditation, or breathing exercises
Some people may benefit from magnesium supplements—talk to your CAR T-cell therapy and health care teams before starting any new supplement.
