I’m hoping to connect with others who have IgA lambda multiple myeloma with the t(11;14) translocation, or anyone with t(11;14). My mom has IgA lambda with t(11;14), and I believe she may be approaching progression, so I’m trying to learn as much as possible to help my family make the best decisions regarding which treatments to pursue and in what order. As many of you probably know, t(11;14) is a somewhat unique subtype of myeloma and is classified as standard-risk. However, after doing a significant amount of research and speaking with other patients on different platforms, I’ve heard very mixed experiences with the traditional frontline approach D-VRd followed by transplant. Some people with t(11;14) have told me that treatments such as CAR-T or venetoclax-based therapy ultimately gave them their deepest response or longest remission. I would especially love to hear from anyone here with t(11;14) who has already gone through treatment. Which treatment worked best for you and how long did your remission last? I understand that everyone’s disease and treatment response can be different, but hearing real experiences from people with the same translocation and subtype would mean a lot to me and my family.

About a year after CAR-T, I developed Cutaneous T-cell lymphoma on my leg. It contained CAR+ genetics resulting from CAR-T. It was resolved with Brentuximab and localized radiation. Just as it was resolved, MM reappeared. On Talvey for that. Then a lump on the pad of my thumb was biopsied as CAR+ CTCL. Anyone seen anything like this?

I’ll be staring Isa-K/d soon. Seeing doctor tomorrow. Any advice on what to ask doctor and what are the preparations, what side effects to expect.

Together, we can make a difference for the blood cancer community. This September, your support helps us reach every patient. https://give.healthtree.org/campaign/758471/donate?src=socialmedia_getinvolved #PersonalizedSupport #OwnYourStory #PowerTheCure #HealthTree #BloodCancerAwarenessMonth

Together, we can make a difference for the blood cancer community. This September, your support helps us reach every patient. https://give.healthtree.org/campaign/758471/donate?src=socialmedia_getinvolved #PersonalizedSupport #OwnYourStory #PowerTheCure #HealthTree #BloodCancerAwarenessMonth

my specialist was all excited about this, since i might be relapsing soon....but my local oncologist said that it requires 10 days in the hospital in Seattle.....i live 2+ hours from there. Anybody out there has had this Tx? Any comments?

Please describe the process of a bone marrow transplant.

I’ve been taking Darzalex for six years now. The last two treatments I seem to have developed GI issues: excess gas/bloating, gut gurgling, appetite suppression, and I’ve vomited once each time - from the next day to 7 days later. The evening is the worst. It does seem to take about a week before I start to feel normal again. I do take Benadryl and Tylenol before treatment and Benadryl each night for about 4-5 days after. I have not used any steroids with my treatment for over a year. I also take Zyrtec daily for non-allergenic rhinitis. Additionally, each treatment seems to trigger some sinus issues for a short time. That side effect has been ongoing for quite some time. Am I the only one? Does anything help you?