DRUG: Conditioning Chemotherapy
BIOLOGICAL: Cord blood graft
DRUG: Azacitidine
DRUG: Enasidenib Mesylate
BIOLOGICAL: Cytokine Induced Memory-like Natural Killer Cells
BIOLOGICAL: Interleukin-2
DRUG: Ivosidenib
DRUG: Ruxolitinib
DRUG: Fludarabine
RADIATION: Total-Body Irradiation
PROCEDURE: Donor Lymphocyte Infusion
DRUG: Cyclophosphamide
DRUG: Tacrolimus
DRUG: Mycophenolate Mofetil
PROCEDURE: Hematopoietic Cell Transplantation
DRUG: Melphalan
PROCEDURE: Bone Marrow Aspiration and Biopsy
PROCEDURE: Diagnostic Imaging
PROCEDURE: Biospecimen Collection
DRUG: INCB057643
DRUG: Ruxolitinib
DRUG: DISC-0974
DRUG: AJ1-11095
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration and Biopsy
DRUG: Onvansertib
PROCEDURE: Ultrasound Imaging
BIOLOGICAL: Peripheral Blood Stem Cell Transplant
DRUG: Allopurinol 300 MG
DRUG: Fludarabine
DRUG: Cyclophosphamide
BIOLOGICAL: Bone Marrow Cell Transplant
RADIATION: Total Body Irradiation
DRUG: Sirolimus Pill
DRUG: Mycophenolate Mofetil
DRUG: Nusivertib
DRUG: Ruxolitinib
DRUG: Momelotinib
DRUG: Cytarabine
BIOLOGICAL: Filgrastim
DRUG: Fludarabine
DRUG: Fludarabine Phosphate
DRUG: Ivosidenib
DRUG: Bezuclastinib Tablets (Formulation A)
DRUG: Bezuclastinib Tablets (Formulation B)
DRUG: Placebo Tablets
DRUG: Busulfan
DRUG: Cladribine
DRUG: Fludarabine Phosphate
PROCEDURE: Hematopoietic Cell Transplantation
DRUG: Thiotepa
DRUG: Venetoclax
RADIATION: Total-Body Irradiation
DRUG: Thiotepa
DRUG: Fludarabine
DRUG: Cyclophosphamide
DRUG: Busulfan
PROCEDURE: Allogeneic Bone Marrow Transplantation
DRUG: Tacrolimus
DRUG: Methotrexate
PROCEDURE: Naive T Cell-Depleted Hematopoietic Stem Cell Transplantation
PROCEDURE: Echocardiography
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DRUG: ELVN-001
DRUG: Ruxolitinib
DRUG: Luspatercept
DRUG: Vorinostat
DRUG: Azacitidine Injection
DRUG: TL-895
DRUG: Ruxolitinib
DRUG: olverembatinib
DRUG: Bosutinib
DRUG: Talazoparib
DRUG: pacritinib
DRUG: Azacitidine
OTHER: Laboratory Biomarker Analysis
DRUG: Ruxolitinib Phosphate
DRUG: INCB160058
DRUG: APG-115
DRUG: 5-azacitidine
DRUG: Itacitinib
DRUG: Busulfan
DRUG: Busulfan
DRUG: Fludarabine
RADIATION: Total-body irradiation
DRUG: Cyclophosphamide
DRUG: Melphalan
PROCEDURE: PBSC Hematopoietic Stem Cell Transplantation (HSCT)
PROCEDURE: Bone Marrow Hematopoietic Stem Cell Transplantation
DRUG: Post-transplant Cyclophosphamide
DRUG: Mesna
DRUG: Tacrolimus
DRUG: Mycophenolate Mofetil
OTHER: Patient-Reported Outcomes
DRUG: Ruxolitinib
DRUG: BCR-ABL Tyrosine Kinase Inhibitor (TKI)
DRUG: Peptide-based vaccine
DRUG: Poly ICLC
BIOLOGICAL: Anti-Thymocyte Globulin
DRUG: Cyclophosphamide
BIOLOGICAL: Cytokine-treated Veto Cells
DRUG: Fludarabine
PROCEDURE: Peripheral Blood Stem Cell Transplantation
RADIATION: Total-Body Irradiation
DRUG: TGRX-678
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DRUG: Cytarabine
PROCEDURE: Echocardiography
DRUG: Fludarabine
DRUG: Hydrocortisone Sodium Succinate
BIOLOGICAL: Imetelstat
DRUG: Leucovorin Calcium
PROCEDURE: Lumbar Puncture
DRUG: Methotrexate
PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Cyclophosphamide
DRUG: Cyclosporine
BIOLOGICAL: Filgrastim
DRUG: Fludarabine
DRUG: Mycophenolate Mofetil
DRUG: Mycophenolate Sodium
RADIATION: Total-Body Irradiation
DRUG: Treosulfan
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Echocardiography
PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
PROCEDURE: Positron Emission Tomography
DRUG: Azacitidine
DRUG: Gilteritinib
DRUG: Venetoclax
DRUG: Decitabine
DRUG: Ruxolitinib
DRUG: Fedratinib
OTHER: Questionnaire Administration
DRUG: Pacritinib
DRUG: Asciminib Pediatric formulation group
DRUG: Asciminib Adult formulation group
DRUG: KRT-232
DRUG: Dasatinib
DRUG: Nilotinib
DIETARY_SUPPLEMENT: Ascorbic Acid
DRUG: Carboplatin
DRUG: Cisplatin
DRUG: Cytarabine
DRUG: Dexamethasone
DRUG: Etoposide
DRUG: Gemcitabine Hydrochloride
DRUG: Ifosfamide
OTHER: Laboratory Biomarker Analysis
DRUG: Oxaliplatin
OTHER: Placebo Administration
OTHER: Questionnaire Administration
BIOLOGICAL: Rituximab
DRUG: Decitabine
PROCEDURE: Biospecimen Collection
PROCEDURE: Core Biopsy
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Echocardiography
PROCEDURE: Positron Emission Tomography
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Central Venous Cannula Insertion
PROCEDURE: Portacath Placement
PROCEDURE: Computed Tomography
DRUG: INCA033989
BIOLOGICAL: Allogeneic Natural Killer Cell Line NK-92
BIOLOGICAL: Anti-Thymocyte Globulin
DRUG: Busulfan
DRUG: Clofarabine
DRUG: Cyclophosphamide
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
DRUG: Melphalan
BIOLOGICAL: Rituximab
RADIATION: Total-Body Irradiation
PROCEDURE: Umbilical Cord Blood Transplantation
DRUG: KRT-232
DRUG: TL-895
BEHAVIORAL: CHAMPS-II adapted to adults 60+ years in HCT setting
DRUG: Imetelstat
DRUG: Ruxolitinib
DRUG: Azacitidine
DRUG: Seclidemstat
DRUG: KRT-232
DRUG: TL-895
DRUG: Imetelstat
DRUG: Best Available Therapy (BAT)
DRUG: Venetoclax
DRUG: Fludarabine
DRUG: Busulfan
DRUG: Venetoclax
DRUG: Azacitidine
DRUG: Decitabine/cedazuridine
DRUG: Purified regulatory T-cells (Treg) plus CD34+ HSPC
DRUG: Fludarabine
DRUG: Melphalan
DEVICE: CliniMACS CD34 Reagent System
DRUG: Tacrolimus
DRUG: Cyclophosphamide
DRUG: Plerixafor
DRUG: Filgrastim granulocyte colony-stimulating factor (G-CSF) or equivalent
DRUG: Thiotepa
DRUG: Mycophenolate Mofetil (MMF)
DRUG: Ruxolitinib
DRUG: Avapritinib
DRUG: Decitabine
COMBINATION_PRODUCT: Decitabine/Cedazuridine
BIOLOGICAL: Axatilimab
DRUG: Azacitidine
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration and Biopsy
OTHER: Survey Administration
DRUG: Busulfan
DRUG: Fludarabine
PROCEDURE: PBSC Hematopoietic Stem Cell Transplantation (HSCT)
DRUG: Post-Transplant Cyclophosphamide
DRUG: Mesna
DRUG: Tacrolimus
DRUG: Mycophenolate Mofetil
OTHER: Patient Reported Outcomes
DRUG: Melphalan
RADIATION: Total-body irradiation
DRUG: Cyclophosphamide
DRUG: Elenestinib
DRUG: Placebo
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspirate
DRUG: Cyclophosphamide
DRUG: Cyclosporine
PROCEDURE: Diagnostic Imaging
PROCEDURE: Echocardiography
DRUG: Fludarabine Phosphate
PROCEDURE: Multigated Acquisition Scan
DRUG: Mycophenolate Mofetil
OTHER: Survey Administration
DRUG: Thiotepa
RADIATION: Total-Body Irradiation
PROCEDURE: Umbilical Cord Blood Transplantation
PROCEDURE: TCRαβ+/CD19+ depleted Haploidentical HSCT
DRUG: Zoledronate
DRUG: Decitabine
DRUG: Listaftoclax
DRUG: Olverembatinib
DRUG: Decitabine and Cedazuridine
DRUG: Venetoclax
BIOLOGICAL: OrcaGraft (Orca-Q)
DRUG: Cladribine
DRUG: Cytarabine
DRUG: Gilteritinib
DRUG: Idarubicin
OTHER: Laboratory Biomarker Analysis
DRUG: Midostaurin
DRUG: Venetoclax
DEVICE: CliniMACS
DRUG: Dasatinib
DRUG: Imatinib Mesylate
OTHER: Laboratory Biomarker Analysis
DRUG: Nilotinib
BIOLOGICAL: Pembrolizumab
DRUG: Bomedemstat
DRUG: Anagrelide
DRUG: Busulfan
DRUG: Interferon alfa/pegylated interferon alfa
DRUG: Ruxolitinib
PROCEDURE: Biospecimen Collection
DRUG: Olutasidenib
DRUG: Azacitidine
DRUG: Venetoclax
DRUG: Ruxolitinib
DRUG: Tasquinimod
DRUG: Azacitidine
DRUG: Venetoclax
DRUG: bezuclastinib
DRUG: Azacitidine
DRUG: Enasidenib
OTHER: Quality-of-Life Assessment
DRUG: Canakinumab
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DRUG: Cytarabine
PROCEDURE: Echocardiography
DRUG: Fludarabine
DRUG: Granulocyte Colony-Stimulating Factor
DRUG: Idarubicin
PROCEDURE: Multigated Acquisition Scan
DRUG: Pivekimab Sunirine
BIOLOGICAL: Orca-Q
DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
DRUG: Azacitidine
DRUG: Quizartinib
DRUG: Ruxolitinib
PROCEDURE: Allogeneic Stem Cell Transplantation
DRUG: Levetiracetam
DRUG: Eltrombopag
DRUG: Busulfan
DRUG: Romiplostim
DRUG: Fludarabine phosphate
DRUG: Cyclophosphamide
DRUG: Mesna
DRUG: Tacrolimus
DEVICE: Miltenyi CliniMACS Prodigy ® system
DRUG: Tagraxofusp
DRUG: Hyperbaric oxygen
DRUG: Azacitidine
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
DRUG: Cytarabine
DRUG: Daunorubicin Hydrochloride
PROCEDURE: Echocardiography
DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
PROCEDURE: Multigated Acquisition Scan
DRUG: Venetoclax
PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
DRUG: Ruxolitinib
DRUG: Selinexor 60 mg
DRUG: Selinexor 40 mg
DRUG: Ruxolitinib
DRUG: Pacritinib
DRUG: Momelotinib
DRUG: Fludarabine
DRUG: Busulfan
DRUG: Melphalan
DRUG: Rituximab
DRUG: Levetiracetam
PROCEDURE: Haploidentical Bone Marrow/Kidney
DRUG: BLU-263
DRUG: Azacitidine
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DIETARY_SUPPLEMENT: Curcumin/ Demethoxycurcumin/Bisdemethoxycurcumin-containing Supplement
DIETARY_SUPPLEMENT: Piperine Extract (Standardized)
DRUG: Placebo Administration
OTHER: Questionnaire Administration
DRUG: Ivosidenib
DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
DRUG: Pegylated interferon alpha2a
DRUG: Cyclophosphamide
DRUG: JAK Inhibitor
DRUG: Fludarabine
BIOLOGICAL: Recombinant Granulocyte Colony-Stimulating Factor
DRUG: Melphalan
DRUG: Mycophenolate Mofetil
PROCEDURE: Peripheral Blood Stem Cell Transplantation
DRUG: Tacrolimus
RADIATION: Total-Body Irradiation
PROCEDURE: Computed Tomography
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Biospecimen Collection
PROCEDURE: Echocardiography
PROCEDURE: Multigated Acquisition Scan
DRUG: Azacitidine
DRUG: Selumetinib
DRUG: LP-118
DRUG: Bexmarilimab
DRUG: Azacitidine
DRUG: Venetoclax
PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Busulfan
DRUG: Cyclophosphamide
DRUG: Fludarabine
DRUG: Melphalan
DRUG: Methotrexate
DRUG: Mycophenolate Mofetil
DRUG: Ruxolitinib
DRUG: Tacrolimus
RADIATION: Total-Body Irradiation
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography
PROCEDURE: Bone Marrow Aspiration and Biopsy
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Ultrasound Imaging
DRUG: Givinostat
DRUG: Hydroxyurea
BIOLOGICAL: Blinatumomab
DRUG: Cytarabine
DRUG: Methotrexate
DRUG: Ponatinib
DRUG: Jaktinib Hydrochloride Tablet
DRUG: Selinexor
DRUG: Selinexor
OTHER: Placebo
DRUG: Ruxolitinib
DRUG: Asciminib
DRUG: Ascimininb + Nilotinib
DRUG: Asciminib + Imatinib
DRUG: Asciminib + Dasatinib
DRUG: TL-895
DRUG: Placebo
OTHER: Laboratory Biomarker Analysis
DRUG: Ponatinib Hydrochloride
OTHER: Quality-of-Life Assessment
DRUG: SLN124
DRUG: Placebo
DRUG: ABL001
DRUG: Dasatinib
DRUG: Prednisone
DRUG: Blinatumomab
DRUG: Asciminib 40 MG
DRUG: Asciminib 40 MG Twice Daily
DRUG: Asciminib 80 MG daily
DRUG: Imatinib
DRUG: Nilotinib
DRUG: Dasatinib
DRUG: Fludarabine
DRUG: Cyclophosphamide
RADIATION: Total Body Irradiation
DRUG: Cyclosporine A
DRUG: Mycophenylate mofetil
BIOLOGICAL: Umbilical cord blood
DRUG: INCB000928
DRUG: ruxolitinib
DRUG: NTX-301
DRUG: Clofarabine
DRUG: Fludarabine
DRUG: Busulfan
DRUG: Cyclosporine-A
DRUG: Mycophenolate Mofetil
BIOLOGICAL: Cord Blood Graft
DRUG: Navtemadlin
DRUG: Navtemadlin placebo
DRUG: Ruxolitinib
DRUG: Edetate Calcium Disodium
DIETARY_SUPPLEMENT: Multivitamin
DRUG: Succimer
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Biopsy
DRUG: Decitabine and Cedazuridine
DRUG: Venetoclax
DRUG: Inqovi
BIOLOGICAL: CD4CAR
DRUG: Asciminib
OTHER: Imatinib Mesylate, Dasatinib, Nilotinib or Bosutinib Withdrawal
DRUG: Imatinib Mesylate, Dasatinib, Nilotinib or Bosutinib Re-initiation
DRUG: Ruxolitinib
DRUG: EAGD T-cell infusion (Phase I)
DRUG: EAGD T-cell infusion (Expansion)
DEVICE: CliniMACS Cell Processing System for TCRαβ + T Cell and CD45RA Depleted Peripheral Stem Cell Addback
RADIATION: Total-Body Irradiation
DRUG: Thiotepa
DRUG: Fludarabine
DRUG: Tacrolimus
BIOLOGICAL: Allogeneic CD34+-enriched and CD45RA-depleted PBSCs
DRUG: Methotrexate
DRUG: Cyclophosphamide
BIOLOGICAL: Peripheral Blood Stem Cell
DRUG: Cyclosporine
DRUG: Sirolimus
DRUG: Busulfan
PROCEDURE: Bone Marrow Aspiration and Biopsy
PROCEDURE: Echocardiography
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Biospecimen Collection
DRUG: CFI-400945
DRUG: Azacitidine
DRUG: Decitabine
BIOLOGICAL: Tagraxofusp-erzs
DRUG: Pacritinib
DRUG: Azacitidine
PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
PROCEDURE: Biospecimen Collection
DRUG: Granulocyte Colony-Stimulating Factor
DRUG: Hematopoietic Cell Transplantation Conditioning Regimen
BIOLOGICAL: Multi-peptide CMV-Modified Vaccinia Ankara Vaccine
PROCEDURE: Pheresis
DRUG: Placebo Administration
DRUG: Stem Cell Mobilization Therapy
DRUG: CK0804
DRUG: Asciminib single agent
DRUG: Imatinib
DRUG: Nilotinib
DRUG: Bosutinib
DRUG: Dasatinib
DRUG: Cladribine
DRUG: Cytarabine
DRUG: Venetoclax
DRUG: Azacitidine
DRUG: PRT2527
DRUG: Zanubrutinib
DRUG: Venetoclax
DRUG: decitabine
DRUG: spartalizumab
DRUG: sabatolimab
DRUG: azacitidine
DRUG: venetoclax
DRUG: INQOVI (oral decitabine)
DRUG: EP31670
DRUG: Gemtuzumab Ozogamicin
DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
OTHER: Quality-of-Life Assessment
DRUG: Cobimetinib
BIOLOGICAL: Dilanubicel
DRUG: Cyclophosphamide
DRUG: Fludarabine
DRUG: Thiotepa
RADIATION: Total-Body Irradiation
PROCEDURE: Umbilical Cord Blood Transplantation
OTHER: Laboratory Biomarker Analysis
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspirate
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Electrocardiography
PROCEDURE: Computed Tomography
DRUG: Trametinib
DRUG: Azacitidine
DRUG: Fludarabine
DRUG: Cytarabine
DRUG: Ascentage Pharma HQP1351 bioavailable inhibitor
DRUG: Blinatumomab
DRUG: Darzalex Faspro (Daratumumab and hyaluronidase-fihj)
DEVICE: JH-DSA Semi-Quant Screen and Response Score
DRUG: Vactosertib
DRUG: Fludarabine Phosphate
DRUG: Cyclophosphamide
DRUG: IL-2
DRUG: Natural Killer Cells
DRUG: Cyclophosphamide
DRUG: Mesna
DRUG: Filgrastim
DRUG: Melphalan
DRUG: Fludarabine phosphate
DRUG: Tacrolimus
DRUG: Mycophenolate mofetil
DRUG: Total Body Irradiation One Dose
DRUG: reparixin
DRUG: JNJ-88549968
DRUG: BGB-11417
DRUG: Azacitidine
DRUG: Posaconazole
DRUG: BGB-11417
DRUG: BGB-11417
DRUG: FHD-286
DRUG: Low Dose Cytarabine
DRUG: Decitabine
BIOLOGICAL: Canakinumab
DRUG: KRT-232
DRUG: Best Available Therapy (BAT)
DRUG: sapablursen
DRUG: Bomedemstat
DRUG: Cladribine
DRUG: Cyclophosphamide
DRUG: Cyclosporine
DRUG: Cytarabine
BIOLOGICAL: Filgrastim
PROCEDURE: Hematopoietic Cell Transplantation
DRUG: Mitoxantrone
DRUG: Mycophenolate Mofetil
DRUG: Mycophenolate Sodium
RADIATION: Total-Body Irradiation
DRUG: Idarubicin
DRUG: Fludarabine
DRUG: Cytarabine
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Echocardiography
PROCEDURE: X-Ray Imaging
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Biospecimen Collection
DRUG: N-Acetylcysteine
BIOLOGICAL: DSP107
DRUG: Azacitidine
DRUG: Venetoclax
DRUG: MGD024
DRUG: Dasatinib
DRUG: Decitabine and Cedazuridine
DRUG: Azacitidine
DRUG: Ivosidenib
DRUG: Venetoclax
DRUG: Luspatercept
DEVICE: Magnetic-Activated Cell Sorter (CliniMACS, Miltenyi)
BIOLOGICAL: HSCT with TBI Regimen
BIOLOGICAL: HSCT with Non-TBI Regimen
DRUG: Tuspetinib
DRUG: Venetoclax Oral Tablet
DRUG: Azacitidine for Intravenous Infusion
Get the latest thought leadership on your Myeloproliferative Neoplasm delivered straight to your inbox
Subscribe to the weekly newsletter for news, stories, clinical trial updates, and helpful resources and events with cancer experts.