Learn about all myeloma happenings on the new Myeloma Crowd site: the first comprehensive site for myeloma patients and caregivers. Dr. Jonathan Licht, MD Northwestern University Robert H. Lurie Comprehensive Cancer Center Interview date: April 11, 2014

 Dr. Licht shares a deep dive into high risk myeloma with an emphasis on the 4;14 mutation that triggers the overproliferation of the MMSET gene. Dr. Licht describes how MMSET affects the cells and his work to screen 100,000 compounds against that gene to find targets that impact MMSET effectively. He describes the relationship between the MMSET and MYC genes and how MMSET promotes MYC growth. He shares how cell signaling pathway treatments, like MEK inhibitors and BRAF inhibitors are being studied to change the signaling for cancer growth for high risk and normal risk myeloma as well.    The live mPatient Myeloma Radio podcast with Dr. Jonathan Licht