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Allogeneic Hematopoietic Progenitor Cell Transplantation From Unrelated Donors


The purpose of this study is to provide an opportunity for patients with malignancies or bone marrow failure states who lack a suitable sibling donor to undergo allogeneic hematopoietic progenitor cell transplantation using cells from unrelated individuals or cord blood registries.same

Trial Eligibility

Inclusion Criteria: > 18 years of Age < 70 years ECOG performance status 0, 1 or 2 Left Ventricular Ejection Fraction > 30% Creatinine clearance > 40ml/min Transaminases < 2X normal Total bilirubin < 2X normal HIV seronegativity Weight < 70kg for cord blood transplantation Ability to cover the cost of the transplant, necessary medications, and transportation/housing. Caregiver must be available while outpatient Exclusion Criteria: Greater than one antigen mismatch at HLA-A, B, C or DR plus one allele mismatch at HLA-A, B, C or DR

Study Info


Scripps Health

Primary Outcome

Bone Marrow and Peripheral Blood Chimerism

Outcome Timeframe 30 days post-transplant

NCTID NCT01364363

Phase Not Applicable

Primary Purpose Treatment

Completion Date July 2015


Procedure Allogeneic transplantation

Locations Recruiting

Scripps Green Hospital

United States, California, La Jolla

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