Hello I am 11 months post SCT After about 4 mos of 5mg daily lenalidomide (Revlimid) maintenance I developed a rash. It started as looking like a heat rash around my waist and developed into a whole body rash, looking like textured reddened skin. It itches a lot, especially if I’m hot. My docs took me off of maintenance for several weeks and gave me a prednisone pack which helped greatly. The rash returned but at a turned down level. I am now back to taking Rev every other day and using prescription lotion. It does seem a bit worse since being back on the Rev. At this point my docs are taking a wait and see approach. I know this is a common side effect. Does anyone have any insights or experiences to share. Other than this challenge things are going well for me and I am back to my normal activities Thank you !

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Well I am thinking I’m headed to a relapse. I got my bloodwork results today and my kappa is 21.4 and my ratio is in the 2 range. My ratio has been a little elevated for three months but went down in August. In July my bmb was good. less than 1%. Is there any reason besides a relapse that my numbers could be off?

Hi all. I am currently on treatment of Isa KD Isatuximab, Carfilzomib and Dex, only got 2 1/2 years of remission after SCT. I’m doing ok with the treatment every week at first now 3 weeks on and one week off. I’m on my Third round, I’ve had some vomiting the night of the treatment, so now I take a ondansetron the day of. But I’m getting night sweats and hot flushes most nights? I’m 59 years old and on HRT have been for 8 years so it’s not menopause? The night sweats started coming back, when my numbers started rising, which I think is normal, but my numbers are back to normal now, so I expected this to stop? Has anyone else had this experience? My worry is that it could be a secondary cancer? Nights sweats are a symptom of cancer.

I need help! Lots of help! I got my first cancer from 911, I worked for the federal gov. I didn't know, and also I was scared to death, by the time they found it it was a stage 4!!! Just like Farrah Faccett,and she died, I just kept suffering. Let me tell you, as my life started very hard, I was unwanted. And my nerves were a wreck! After the first cancer, than a heart attack also from 911, and Let's not for get the myltuipy myloma, which seems to come and go???? I don't believe they want to treat me because of my age,, I can't walk well enough to work my brain is mixed up, I keep going to drs. Who know less than I do, like no one care. Tomorrow, I want my mbloodmdrawn imwant to dpsee if it is getting better, worse or just staying the same. One dr. Ind, wants to put me on medicine, the dr, in Tampa say no need for treatment yet, keep,watching, but they found it in my bone morrowm2x and tell me it don't go away . So can I say I was dignised on2018 and now it's 2026,that is 8 years, how can it vibe in your bones, and than one day, it's just going to explode like it did to,my friend and my doctor,mthry had there lastm6 months in Hell. Please,I need help,with all this, what can I do I can't walk it hurts so much and I need a job .

My mom was just diagnosed yesterday with IgG Lambda Multiple Myeloma with high-risk cytogenetics (del17p – 7%, gain 1q – 6%) from a oncologist/hematologist. We want to start induction treatment ASAP, but the soonest myeloma specialist appointment is late November. The oncologist (not a specialist) has recommended quadruplet Dara-VRd as induction therapy. My questions for the group: - How critical is it to see a myeloma specialist before starting induction therapy? - Has anyone compared Dara-VRd vs Dara-KRd, especially for high-risk patients? - Are there any other induction therapy options we should consider before moving forward? I really would appreciate any help as I am freshly new to navigating all of this. Thank you all so much!

Have anyone that taken Chemo with low platelet and red blood cells tried the papaya extract leaves if so did it work to bring them back up

Hi all, I’m Lucy, I was diagnosed with AML last year June ‘24, aged 38. I’m recovering from an allo stem cell transplant last November ‘24. Gratefully I should be cured (unless I relapse). I had to move from Bermuda to Boston, USA for treatment and I expect to be here til Nov when I celebrate my first re-birthday after SCT. My mother moved with me as I’d never want to go through this alone. It was a big adjustment leaving the rest of my family and friends (and cat!) as well as losing my job as my recovery took too long 🙄 I feel like my life is on pause and I forget that everyone else is carrying on as normal. Did others have complete changes in living arrangements or have to move far for treatment? Or relate to other aspects? Also any tips on hair regrowth? My hair has been growing for 6 months and missed the “cute chemo curls” memo - any advice on taming my “mangy rat met electric socket” look is welcomed!

From Amyloidosis Foundation A recent 15-year analysis from ashpublications.org reveals a significant decline (71%) in autologous stem cell transplantation (ASCT) for AL amyloidosis as Dara-CyBorD (daratumumab, cyclophosphamide, bortezomib, dexamethasone) replaced CyBorD (cyclophosphamide, bortezomib, dexamethasone) as the preferred upfront therapy. The study indicates ASCT is now reserved for patients with relapsed/refractory disease, suboptimal responses to Dara-CyBorD, or high bone marrow plasma cell burden. Key Findings: Shift from ASCT to Dara-CyBorD: . The introduction of Dara-CyBorD led to a substantial decrease in ASCT utilization, with a 71% reduction observed between the CyBorD-dominated era (2010-2019) and the Dara-CyBorD era (2020-2024). Increased Pre-ASCT Therapy: . In the more recent cohort, a higher percentage of patients received pre-ASCT induction therapy, with Dara-CyBorD being the prevalent choice. Improved Response Rates: . Dara-CyBorD demonstrated superior hematologic response rates compared to CyBorD, contributing to its reduced reliance on ASCT as a salvage therapy. ASCT for Refractory/High-Risk Cases: . ASCT is now primarily utilized for patients who don't respond adequately to Dara-CyBorD, patients with relapsed or refractory disease, or those with a "myeloma phenotype" characterized by a high plasma cell burden in the bone marrow. Patient Profile Changes: . The study also noted some changes in the characteristics of patients undergoing ASCT in the later period, including older age and a higher baseline bone marrow plasma cell burden.

I have soldering myeloma, MDS and siderblasttic anemia along with fibromyalgia. Should I go on hospice. I was first diagnosed over 5 years ago.

HI I need solution for this My Grandfather has diagnosed as AML I think he is in initial stage. I am his grandson we asked many hospitals in our surroundings no is responding and treating him properly and not admitting him. Due to age reasons. He is almost 90 years old. He are suffering a lot. Not having food. Properly and i can't see him like that I am seeking suggestion to extend his life span and ways to do this we are family of poor not rich. we are seeking for support please help to to find solution