Lymphoma CAR T-cell Therapy Guide

In this section, you will learn about the purpose of this guide and how to navigate it.

In this section of the guide, learn how CAR T-cell therapy for lymphoma works.

Learn about the surface proteins that lymphoma CAR T-cell therapies target.

Learn about the difference between CAR T-cell therapy and a stem cell transplant.

Learn factors that doctors consider when recommending CAR T-cell therapy for people with lymphoma.

Learn which people with lymphoma are eligible for CAR T-cell therapy.

Learn about clinical trials that test CAR-T as an earlier treatment option for lymphoma.

Learn what to consider before CAR T-cell therapy for lymphoma.

Learn about the benefits and barriers to CAR T-cell therapy for lymphoma.

Learn about the FDA-approved CAR T-cell therapies for people with lymphoma.

Learn about the FDA-approved CAR T-cell therapies for people with follicular lymphoma.

Learn about the FDA-approved CAR T-cell therapies for people with large B-cell lymphoma (LBCL).

Learn about the FDA-approved CAR T-cell therapies for people with mantle cell lymphoma (MCL).

Learn about the FDA-approved CAR T-cell therapies for people with marginal zone lymphoma (MZL).

Learn about the FDA-approved CAR T-cell therapy for small lymphocytic lymphoma (SLL)/chronic lymphocytic leukemia (CLL).

Learn why common side effects of CAR T-cell therapy happen and how they are managed for people with lymphoma.

Learn why cytokine release syndrome (CRS) happens from CAR T-cell therapy and how it is managed.

Learn what neurotoxicity and ICANS are, why they sometimes happen from CAR T-cell therapy for lymphoma, and how they are managed.

Learn why low blood counts happen from CAR T-cell therapy for lymphoma and how they are managed.

Learn why infections happen after CAR T-cell therapy for lymphoma and how they are managed.

Learn about the digestive or gastrointestinal (GI) side effects of CAR T-cell therapy for lymphoma and how they are managed.

Learn why fatigue happens after CAR T-cell therapy for lymphoma and how to manage it.

Learn why muscle, joint, and bone pain happen after CAR T-cell therapy for lymphoma and how to manage them.

Learn about newer types of CAR T-cell therapies for lymphoma in clinical trials.

Helping your loved one prepare for and recover from CAR T-cell therapy can be challenging. This section outlines ways the patient may need support and offers tips to help you in your role as their care partner.

Learn how your loved one with lymphoma may need help from a care partner during CAR-T therapy. Knowing what to expect can help you feel more prepared for the role.

Caring for someone receiving CAR T-cell therapy can be demanding. Learn strategies to help care partners stay healthy while supporting their loved one.

Many people wonder if they can still receive CAR T-cell therapy without a full-time caregiver. The good news is that there are solutions, and not having a caregiver does not automatically disqualify you from treatment.

This section helps you understand how to talk with your healthcare team about chimeric antigen receptor (CAR) T-cell therapy for lymphoma. You’ll learn what questions to ask, what to expect, and how to make informed decisions about this treatment.

Knowing when to bring up CAR T-cell therapy as a treatment option can help ensure it's discussed at the right time.

Discover questions you can ask your doctor about CAR T-cell therapy for lymphoma.

Sometimes, going to a healthcare appointment alone can feel overwhelming. Having a loved one come with you can help carry some of the weight when addressing all concerns and questions.

Getting another expert’s perspective can offer peace of mind and ensure you’re making the most informed decision for your unique situation.

When discussing complex treatments like CAR T-cell therapy, it’s easy to feel overwhelmed. Staying organized helps you make decisions with more confidence and clarity.

Open communication with your care team is essential, especially when navigating complex treatments like CAR T-cell therapy. If you have questions, concerns, or if something doesn’t feel right, don’t hesitate to speak up.

If you’re considering transferring to a different health care team or center, learn about the steps you need to take.

Recovery after CAR T-cell therapy for lymphoma takes time as your immune system slowly rebuilds. The first 30 days after the infusion are considered the acute recovery period.

For the first month after the CAR-T infusion, you will have at least weekly appointments to check blood counts and manage any side effects.

People with lymphoma often report that finances are one of the biggest concerns for CAR T-cell therapy.  Discover financial resources that may help you manage CAR-T costs.

Learn how medicare coverage works for lymphoma CAR T-cell therapies.

Learn about pharmaceutical company assistance programs for lymphoma CAR T-cell therapies.

Explore additional financial resources for lymphoma CAR T-cell therapy.

This section contains additional resources that might be helpful as you learn more about CAR T-cell therapy for lymphoma.

We invite you to read the sources below to learn more about CAR T-cell therapy for lymphoma.

This resource list also acts as a reference for this guide, as much of the material referenced was used to create the content.