DRUG: Fludarabine

RADIATION: Total-Body Irradiation

PROCEDURE: Donor Lymphocyte Infusion

DRUG: Cyclophosphamide

DRUG: Tacrolimus

DRUG: Mycophenolate Mofetil

PROCEDURE: Hematopoietic Cell Transplantation

DRUG: Melphalan

PROCEDURE: Bone Marrow Aspiration and Biopsy

PROCEDURE: Diagnostic Imaging

PROCEDURE: Biospecimen Collection

DRUG: INCB057643

DRUG: Ruxolitinib

DRUG: AJ1-11095

DRUG: DISC-0974

DRUG: Peptide-based vaccine

DRUG: Poly ICLC

DRUG: Azacitidine

OTHER: Laboratory Biomarker Analysis

DRUG: Ruxolitinib Phosphate

DRUG: Talazoparib

DRUG: pacritinib

DRUG: Ruxolitinib

DRUG: Decitabine

DRUG: Ruxolitinib

DRUG: Fedratinib

OTHER: Questionnaire Administration

DRUG: Pacritinib

DRUG: Bomedemstat

DRUG: Anagrelide

DRUG: Busulfan

DRUG: Interferon alfa/pegylated interferon alfa

DRUG: Ruxolitinib

DRUG: INCA033989

DRUG: Ruxolitinib

DRUG: Tasquinimod

PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation

DRUG: Liposome-encapsulated Daunorubicin-Cytarabine

DRUG: Ruxolitinib

DRUG: KRT-232

DRUG: TL-895

DRUG: Methotrexate (MTX)

DRUG: Bomedemstat

DRUG: Hydroxyurea

DRUG: Bomedemstat placebo

DRUG: Hydroxyurea placebo

PROCEDURE: Biospecimen Collection

PROCEDURE: Bone Marrow Aspiration

PROCEDURE: Bone Marrow Biopsy

DIETARY_SUPPLEMENT: Curcumin/ Demethoxycurcumin/Bisdemethoxycurcumin-containing Supplement

DIETARY_SUPPLEMENT: Piperine Extract (Standardized)

DRUG: Placebo Administration

OTHER: Questionnaire Administration

DRUG: Jaktinib Hydrochloride Tablet

DRUG: KRT-232

DRUG: Best Available Therapy (BAT)

DRUG: JNJ-88549968

DRUG: reparixin

DRUG: Bomedemstat

DRUG: N-Acetylcysteine