BETA - Is my family at risk of developing chronic lymphocytic leukemia?

Is my family at risk of developing chronic lymphocytic leukemia? So in most of the cases that we see in our clinics, CLL is not familial or genetic. That means transmitted from one family or runs in the family. Put it in simple layman's terms, it does not run in the family in most of the patients. However, there's a small number of patients, less than 10% of the patients, who have a family member, first degree or second degree family member, with a history of CLL. Those CLLs are considered familial. As far as genetics of familial CLL, we do not know enough about that. There is no founder mutation. So as far as testing family members for the genetic predisposition, there is no specific test for that. For the patients who have a family member with a history of CLL and are diagnosed, there are more than one or two family members with CLL. There's no specific guidelines of what they should be doing. Just like any one of us, we should be seeing a physician for annual physical examination once a year. That's all that's recommended. Nothing beyond that at this point. Chronic lymphocytic leukemia occur in a higher percentage in patients who have first degree family relatives who have CLL. It does occur in a slightly increased percentage in those patients who have family members. But it does not necessarily mean that all of the siblings or all of the children of a patient will also have CLL.