What are the different types of diffuse large B-cell lymphoma?
So there are different subtypes of diffuse large B-cell lymphoma. And then there are different ways that we categorize diffuse large B-cell lymphoma once we have that basket diagnosis based on different pathological features. So there's diffuse large B-cell lymphoma. There's an aggressive B-cell lymphoma called primary mediastinal B-cell lymphoma. There's post-transplant lymphoproliferative disorder that can be a type of diffuse large B-cell lymphoma. There's an intravascular subtype of diffuse large B-cell lymphoma. There's a diffuse large B-cell lymphoma specifically associated with EBV called EBV-positive diffuse large B-cell lymphoma.
There’s also, you know, to name some of the different subtypes, once you diagnose somebody with diffuse large B-cell lymphoma there is also different molecular features of aggressive lymphoma that can help determine maybe how a patient would be treated, particularly in the relapse setting or what treatments they may or may be more sensitive. So there’s specific things that are sometimes mentioned like GC, or germinal center diffuse large B-cell lymphoma or non GC or ABC type diffuse large B-cell lymphoma. And then there's diffuse large B-cell lymphomas associated with certain chromosomal translocations of the lymphoma that can help predict what treatment a physician might choose.