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What are the Signs and Symptoms of DLBCL?

A symptom is a manifestation of the illness that the patient experiences and the doctor does not see. A sign is a manifestation of the illness that the doctor is able to see. 

Most DLBCL patients experience some of the below signs and symptoms of the disease. Reach out to a DLBCL specialist if you experience any of the following: 

  • Frequent infections
  • Swollen lumps on sides of neck, underarms, or groin area (swollen lymph nodes)
  • Persistent tiredness, shortness of breath, and pale skin (anaemia) 
  • Easy bleeding and bruising
  • Fever and night sweats
  • Unintentional weight loss
  • Enlarged spleen and/or liver

The reason DLBCL patients may experience the above signs and symptoms is because DLBCL cells are mutated B-cells. B-cells are created in the bone marrow (which are then released into the bloodstream) and the lymph system. When DLBCL cells multiply in those areas, they can build up in the lymph system nodes and organs making them swell. The cancer cells may crowd out other needed blood cells like white blood cells (protect body against infections), red blood cells (carry oxygen to parts of the body which if low patient can experience symptoms of anaemia), and platelets (fix wounds, if low patient can bruise and bleed easily). DLBCL cells tend to multiply quickly and patients need treatment at the time of diagnosis. There are effective treatment options to manage the disease for many patients. See here for treatment options for DLBCL patients. 

If you experience any of the above signs or symptoms, reach out to your DLBCL specialist immediately to determine the best treatment path. Need help finding a specialist? Visit HealthTree's DLBCL Specialist Directory

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