Bortezomib-Induced Peripheral Neuropathy in Multiple Myeloma: A Research Roundtable on Patient Experiences and Long-Term Impact image

Bortezomib-Induced Peripheral Neuropathy in Multiple Myeloma: A Research Roundtable on Patient Experiences and Long-Term Impact

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Dec 18, 2026
02:00PM - 03:00PM EST
Online Event
Overview

Join us for an informative and supportive roundtable designed for multiple myeloma patients and caregivers as we share critical findings from a recent patient-centered research study on bortezomib-induced peripheral neuropathy (BIPN). Led by study investigators Dr. Rafael Fonseca, Dr. Valentina Cardenas, Jay Hydren, PhD, from the HealthTree Foundation, alongside patient participants, this session focuses on understanding the lived patient experience and daily functional impact of neuropathy. Rather than viewing neuropathy as merely a temporary or easily managed side effect, the discussion highlights real-world evidence showing that BIPN is frequently long-lasting or permanent, even with modern weekly and subcutaneous dosing.

Grounded in authentic patient voices and survey data from over 300 individuals, the panel will explore how nerve symptoms intersect with mobility, sleep, independence, and overall quality of life. The conversation will examine the hidden day-to-day challenges (such as balance issues, fear of falling, and career changes) while addressing the gaps in clinician symptom grading, anticipatory counseling, and the role of alternative proteasome inhibitors. Whether you are navigating neuropathy yourself, preparing for treatment, or supporting a loved one, you will gain practical insights and vocabulary to help you feel empowered during conversations with your care team.

Agenda
2:00 PM
Introductions
Cynthia Cahoon, RN

Cynthia introduces the agenda of the event and our featured speakers Dr. Rafael Fonseca, Dr. Valentina Cardenas Castro, & Jay Hydren, PhD

2:05 PM
Presentation
Dr. Rafael Fonseca, Dr. Valentina Cardenas Castro, & Jay Hydren, PhD

Our guest panel shares critical findings on peripheral neuropathy (BIPN).

2:35 PM
Questions and Answers
Audience

Come with your questions we will answer them!

Speakers & Moderators
Healthtree contact Cynthia Cahoon, RN

Cynthia Cahoon, RN

Cynthia is a newborn ICU nurse by trade that has spent the last six years in the medical device industry educating nurses and doctors about devices that are new to their facility. In her spare time she enjoys hiking, traveling the world with her family, and creating Halloween animatronics for her annual front yard display. She has a passion for life-long learning and enjoys sharing what she learns with the people around her.
Healthtree contact Rafael Fonseca, MD

Rafael Fonseca, MD

Rafael Fonseca, MD, is the Getz Family Professor of Cancer, Professor of Medicine, interim Executive Director of the Mayo Clinic Comprehensive Cancer Center, Director for Innovation and Transformational Relationships, and a consultant in the Division of Hematology/Oncology at the Mayo Clinic in Arizona. Dr. Fonseca’s practice has focused on the diagnosis and treatment of plasma cell disorders and leading the multiple myeloma team in its effort to understand the disease and its impact on patients. In his laboratory, Dr. Fonseca has led his team of researchers in concentrating on the genetic nature of the clonal cells of plasma cell disorders. He is also interested in myeloma bone disease, prognostic markers and development of new therapies. Throughout his training and career, Dr. Fonseca has received numerous awards and honors, including the Young Investigator Award in Hematology (Celgene – Achievement Awards for Clinical Research in Hematology), the Damon Runyon-Walter Winchell Clinical Investigator Award, and the International Waldenström Macroglobulinemia Research Award. Most notably, he is a Mayo Clinic Distinguished Investigator, the highest academic distinction given to investigators at his institution. Dr. Fonseca holds memberships and serves in positions for organizations such as the American Society of Clinical Oncology, the American Society of Hematology, the American Association for Cancer Research, and the International Myeloma Society. His research has been funded by the National Cancer Institute (R01, P01, SPORE), the Leukemia and Lymphoma Society, the Multiple Myeloma Research Fund, and the Damon Runyon Cancer Research Fund, for which he also serves as a clinical investigator. Dr. Fonseca serves as reviewer and in editorial capacities for medical publications including Blood, Lancet, Nature Medicine, Cancer Cell, Leukemia, and the New England Journal of Medicine, among others. He is a frequent reviewer of grants and sits on the SPORE grant review panel. He has given many national and international presentations as a visiting professor and has authored more than 300 articles, book chapters, editorials, abstracts, and letters.
Healthtree contact Jay Hydren, PhD, CSCS

Jay Hydren, PhD, CSCS

I’m a clinical researcher, with over 15 years of experience investigating various aspects of human health, nutrition and physiology. My PhD encompassed the broad topics of nutrition and integrative physiology with particular focus on age related diseases and vascular health. My most recent work focuses on accelerating a cure and treatments for Multiple Myeloma. I’m also working to improve patient experiences and decision-making processes for cancer treatment and care. To complement these critical research efforts, I enjoy hiking and skiing in Utah and surrounding states, along with training my dog and digital photography.