BETA - What are some shortcomings (limitations) of the results obtained from a bone marrow biopsy (BMB) test? What is a liquid biopsy?

BETA - What are some shortcomings (limitations) of the results obtained from a bone marrow biopsy (BMB) test? What is a liquid biopsy?
What techniques are used to monitor measurable residual disease and how accurate are the results?
What does it meant to be MRD negative? What does this mean for my long term outcomes?
What does it mean to be MRD positive? What does this mean for my long term outcomes?
What specifically in the sample is measured in order to determine MRD status?
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