Here is a new one (at least to me). About three months ago my left ankle started swelling, and hurting when I walked. Hurt more when I lifted my for to take a step. Got a referral to an ortho/oncologist who took X-rays and his first "diagnosis" was I probably broke it in Feb when I fell in the garage and hit directly on my SST knee OR it broke and I fell. He ordered nerve studies as I also have PN in that leg. Of course waited three weeks until he finally got back to me and now said he thought I had torn a ligament -- ice it. And he wanted me to see a podiatrist. Another two weeks, another X-ray, and now voila, he says it all due to walking barefoot and I have flat feet. And Arthritis. Need to get a special brace. You guessed it, two weeks later an appointment to get fitted for an ankle brace --$1500! I ordered a brace online for $40. I said whoa. 1) All these "diagnoses" don't explain the top-of-the-foot pain, the up-the-leg deep pain, the throbbing. So, I waited to talk to my specialist today. I told him the saga since I had last discussed it with him and he shook his head. He looked at the last CAT scan of my ankle and showed me two lytic lesions in the large bone! I didn't know they were there. Dr. A told me of his very bad ankle (he said mine was beautiful compared to his. Walk through the pair, use topicals, and use the Mobix 7.5mg and try to lose weight. (Sounds like he talking to my sister!) My question is, after this LONG explanation, does anyone have suggestions on topicals or what pain relievers you use -- no opiates, please?

I am on 6th treatment plan with oral chemo now. Yesterday I had some kidney function problems that I supposed could be MM. However, after spending the night in emergency rooms in two Charlotte facilities, the problem was related to Prostate. Back home with follow up to see if problem is resolved or more.

Hello everyone, I wanted to ask you about the bone pain, the lytic lesions that occur in MM, the effectiveness of zoledronic acid (zometa), and the fractures that arise during this disease. My dad started with pain in his femur, there is post-relapse wear and tear. He is currently receiving daratumumab (dartzalex), pomalidomide, dexamethasone, gabapentin, fluconazole, acyclovir, etc., but for pain, I can't find anything more practical than tramadol and with fewer side effects. Thanks a lot

If you have had CAR T-Cell Therapy recently or have been a caregiver for someone who had CAR T and would like to participate in a focus group, please see link below. (Interest form: https://www.accc-cancer.org/car-t-survey)

Could someone please give me their experiences with taking Dex? Does everyone gain weight with this drug? Does it make your appetite increase and is that what causes weight gain? If you control your appetite, can you control the weight gain? Thank you.

My request has two parts: 1) Besides searching the HealthTree clinicaI trial search function and SparkCures, I would like to find other sources with clinical trial information, such as NIH and others, and 2) I would appreciate guidance on whether there are medical centers, NIH, etc. that provide compensation for travel and lodging expenses.

Has anyone tried or is on Prolia for osteoporosis? What is your experience and side effects? I have heard and read bad things Can anyone share their experience please