🚨 Recent News in Myeloma Treatment! 🚨 The U.S. FDA has approved Blenrep (belantamab mafodotin-blmf) in combination with Velcade (bortezomib) and dexamethasone (BVd) for relapsed or refractory multiple myeloma. ✨ Based on the DREAMM-7 trial, this new treatment option showed a 51% lower risk of death and extended progression-free survival to 31.3 months compared to 10.4 months with standard care. This approval gives new hope to patients who have received at least two prior lines of therapy. 💪 📌 Learn more about this important advancement 👉 https://healthtree.org/myeloma/community/articles/blenrep-fda-approval?utm_source=social_media&utm_medium=meta&utm_campaign=socialmediaorganic&utm_content=general

Has anyone had Tarvy as pre-treatment before having Car-T Cell therapy ? What was the experience like?

Follow up

I’m interested in information about skin changes that Ive been having. I have lambda light change myeloma that Ive described on another thread. Briefly, I was put ona regime that first started with REVlimid-Dara-dex. Monthly Zometa. Rash caused my oncologist to lower Rev dose. This didn’t help. Put on Pomalyst but shortly went out of remission. Am now on DkD; IVIG and Zometa monthly. During ALL of this (now about 27 weeks since first treatment) I continued to have a rash: small pimples (2-3 mm) with a zone of intense itching that is not visible on the skin surface, that can extend 2-3+ inches. When multiple pimples appear within proximity to others the “zones” overlap and thus the itching is very extensive yet unnoticeable except the dreaded and also itchy pimples. A “Vey” diagram would show the effects. Dermatologist did biopsy: results “severe hypersensitivity to medication.”Ive been treating it with Triamcinolone which offers brief relief. I have always had minor chronic itching since first treatment but a week ago it flared, again—as it does off and on regardless of the treatments, as described above. I see no correlation with any medication. About the time of the this rash flare I began to have “bruising” (what I’ve heard referred to as “liver spots” on older folks). These too began with my first thread but in minor ways. This week however looks a bit like I was beat up. Pictures of both attached. Any thoughts? Thanks! Bob

🎧 New Podcast Alert! In this plain-language episode, we break down the most important highlights from ASCO 2025 and EHA 2025, making complex myeloma updates easier to understand. 🩸 Joined by an expert patient and a myeloma specialist, we cover: MRD-driven strategies Novel immunotherapies Supportive care Precision medicine & AI MRD negativity is becoming a key therapeutic goal, and supportive, personalized care continues to improve outcomes and quality of life for people living with multiple myeloma. 🎙️ Listen now and stay informed! 👉https://open.spotify.com/episode/5u4tj34rjNMzVUdfn6Cln3

I have SMM , diagnosed Aug 2024 Last PET and blood work was good No tumors / lesions / blood stable IGA still very high IGG low month ago But last week or so fatigue has been extreme , bone pain everywhere and waking up with bruises everywhere No falls or reasons for the bruises and vision been blurry and had migraines a couple days . But overall the fatigue is terrible . Should I be concerned of progression ? Anyone else start with Smoldering that progressed to MM that can tell me signs to be aware of ? Thank you

Hello everyone and thank you for having me, in this group my husband, was diagnosed with multiple myeloma, but he’s doing really well now he has had a stem cell transplant and Car-T transplant and is now in remission. I guess we can say but he’s doing great and I thank God every day for his journey.

I’m in a similar situation with Igg numbers particularly low after CAR-T on 12/31/2024. I’ve been taking a monthly IVIG treatment for 6 months now and been illness-free until last week when I contracted Shingles (yes, it sucks and recommend avoiding it if you can). I generally avoid people/crowds out of habit but have been slipping on the mask usage at my typical haunts. Michael

Behind every patient’s fight, there’s a caregiver whose love and strength light the way. 💛 This November, we want to honor you through our “Heart Behind the Care” campaign. If you’re ready to share your story, to inspire, comfort, and bring hope to others, please email ximena@healthtree.org Your story will be shared on HealthTree to celebrate and uplift the caregiver community. Your voice matters. Your story matters. Let’s celebrate caregivers together. TOGETHER WE CARE. TOGETHER WE CURE

I had a kyphoplasty procedure about 2 weeks ago to “fix” a compression fracture in my L4 vertebra. The intense pain from the fracture was relieved immediately after the procedure. What caught me unaware was the excruciating pain throughout my entire rib cage which started the next day and continues 2 weeks later. I still need to take OxyContin extended release pills to manage the pain because acetaminophen doesn’t touch it. Has anyone else had this outcome after a kyphoplasty and how long does it take to go away? Thanks for any helpful suggestions in advance!

Recently diagnosed in August 2025 started treatment 10/14/2025. Pretty intense at first. Pills and injections twice a week. And one week off . Who has had a great outcome with this treatment. Using dexamethasone and valcade injections

Behind every patient’s fight, there’s a caregiver whose love and strength light the way. 💛 This November, we want to honor you through our “Heart Behind the Care” campaign. If you’re ready to share your story, to inspire, comfort, and bring hope to others, please email ximena@healthtree.org Your story will be shared on HealthTree to celebrate and uplift the caregiver community. Your voice matters. Your story matters. Let’s celebrate caregivers together. TOGETHER WE CARE. TOGETHER WE CURE

Behind every patient’s fight, there’s a caregiver whose love and strength light the way. 💛 This November, we want to honor you through our “Heart Behind the Care” campaign. If you’re ready to share your story, to inspire, comfort, and bring hope to others, please email ximena@healthtree.org Your story will be shared on HealthTree to celebrate and uplift the caregiver community. Your voice matters. Your story matters. Let’s celebrate caregivers together. TOGETHER WE CARE. TOGETHER WE CURE

Please note the following from the Patient Advocate Foundation: CPR Funds Now Open: Multiple Myeloma, Myelodysplastic Syndromes The specific eligibility criteria for each fund can be found at https://copays.org/funds/. For personal assistance with the application process please contact us toll-free at 866-512-3861 or visit our application portals at https://portal.copays.org/#/login, with access available for patients, providers, and pharmacies.

Please note the following from the Patient Advocate Foundation: CPR Funds Now Open: Multiple Myeloma, Myelodysplastic Syndromes The specific eligibility criteria for each fund can be found at https://copays.org/funds/. For personal assistance with the application process please contact us toll-free at 866-512-3861 or visit our application portals at https://portal.copays.org/#/login, with access available for patients, providers, and pharmacies.

My husband had a analogous stem cell transplant earlier this year Jan / February for kappa light chain myeloma. He recovered well and is apparently in remission. His kappa cells have recently started rising again in blood test and I'm wondering if its a sign of early relapse. He is on maintenance dose of 10 mg lenalidomide which last week was increased to 15 mg. Im feeling anxious about this. I am a nurse myself so maybe just overthinking things . I emailed the nurse coordinator today and asked her to check with the Dr but he hasn't replied to her. All other bloods are fine at thus stage. Protein a little low. Urea elevated slightly. I appreciate and thoughts on this. Should I be doing more .